Extensive segmental acanthosis nigricans form of epidermal nevus.

Extensive segmental acanthosis nigricans form of epidermal nevus

هیپرکراتوز دو طرفه نیپل و آرئول پستان: گزارش مورد

A 25-year-old woman with a history of five years of bilateral verrucous hyperkeratosis and darkening of both nipples and areolae is reported herein. The histopathology was suggestive of hyperkeratosis of areola and nipple. Hyperkeratosis of areola and nipple is a rare condition which is seen unilaterally or bilaterally in both sexes. Three types of hyperkeratosis of areola and nipple are descri...

A case of nevoid acanthosis nigricans.

Sir, Naevoid acanthosis nigricans (AN) is an extremely rare form of AN that can manifest with a characteristic naevoid appearance at any age before puberty (1 – 3). It is not associated with any known syndrome, endocrinopathy, drugs or internal malignancy (1 – 3) and, thus far, there have been only 2 case reports in the literature of naevoid AN with a unilateral distribution (1, 2). We report a...

Hypochondroplasia, Acanthosis Nigricans, and Insulin Resistance in a Child with FGFR3 Mutation: Is It Just an Association?

FGFR3 mutations cause wide spectrum of disorders ranging from skeletal dysplasias (hypochondroplasia, achondroplasia, and thanatophoric dysplasia), benign skin tumors (epidermal nevi, seborrhaeic keratosis, and acanthosis nigricans), and epithelial malignancies (multiple myeloma and prostate and bladder carcinoma). Hypochondroplasia is the most common type of short-limb dwarfism in children res...

Cutaneous features of Crouzon syndrome with acanthosis nigricans.

IMPORTANCE Crouzon syndrome with acanthosis nigricans is a distinct disorder caused by a mutation in the FGFR3 gene, featuring craniosynostosis, characteristic facial features, and atypical and extensive acanthosis nigricans. Other cutaneous findings have not been thoroughly described. OBSERVATIONS We report 6 cases and summarize the existing literature with regard to the cutaneous manifestat...